Phospho-CSNK1A1/CSNK1A1L (Tyr294) Antibody

Size : 100 µL Clone Number: Aliases: KC1A; CKI-alpha; CSNK1A1; alpha isoform; Casein kinase I Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P48729/Q8N752 Immunogen: Peptide sequence around phosphorylation site of tyrosine 294 (Y-D-Y(p)-T-F) derived from Human CK-1?. Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; WB: 1: 500-1: 1000, IHC: 1: 50-1: 100 Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.Tapia C., FEBS Lett. 349: 307-312(1994).Fish K.J., J. Biol. Chem. 270: 14875-14883(1995).Halleck A., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CSNK1A1/CSNK1A1L Research Areas: Signal transduction?Stem cells