Phospho-CFL1/CFL2 (Tyr88) Antibody

Size : 100 µL Clone Number: Aliases: CFL1/CFL2 Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P23528/Q9Y281 Immunogen: Peptide sequence around phosphorylation site of tyrosine 88 (A-T-Y(p)-E-T) derived from Human coflin1/cofilin2. Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; WB: 1: 500-1: 1000, IHC: 1: 50-1: 100 Background: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1: 1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Carlier, M. et al. (1999) J. Biol. Chem. 274, 33827-33830. Arber, S. et al. (1998) Nature 393, 805-809. Yang, N. et al. (1998) Nature 393, 809-812. Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CFL1/CFL2 Research Areas: Neuroscience?Cancer Cardiovascular;Signal transduction