ARHGEF12 Antibody

Size : 100 µL Clone Number: Aliases: ARHGC_HUMAN antibody; ARHGEF12 antibody; KIAA0382 antibody; leukemia-associated rho guanine nucleotide exchange factor antibody; Leukemia-associated RhoGEF antibody; PRO2792 antibody; Rho guanine exchange factor (GEF) 12 antibody; Rho guanine nucleotide exchange factor (GEF) 12 antibody; Rho guanine nucleotide exchange factor 12 antibody; Similar to Mouse Lsc oncogene antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9NZN5 Immunogen: Synthesized peptide derived from internal of Human ARHGEF12. Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB; WB: 1: 500-1: 3000 Background: May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Kourlas P.J., Proc. Natl. Acad. Sci. U.S.A. 97: 2145-2150(2000). The MGC Project Team, Genome Res. 14: 2121-2127(2004). Nagase T., DNA Res. 4: 141-150(1997). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ARHGEF12 Research Areas: Signal transduction