Phospho-EZR (Tyr478) Antibody

Size : 100 µL Clone Number: Aliases: Villin 2 ezrin antibody; CVIL antibody; CVL antibody; Cytovillin 2 antibody; Cytovillin antibody; DKFZp762H157 antibody; Epididymis secretory protein Li 105 antibody; EZR antibody; EZRI_HUMAN antibody; Ezrin antibody; FLJ26216 antibody; HEL S 105 antibody; MGC1584 antibody; p81 antibody; VIL 2 antibody; VIL2 antibody; Villin 2 (ezrin) antibody; Villin 2 antibody; Villin-2 antibody; Villin2 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P15311 Immunogen: Peptide sequence around phosphorylation site of tyrosine 478 (P-V-Y(p)-E-P) derived from Human Ezrin. Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB; WB: 1: 500-1: 1000 Background: Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis. Murchie R, et al. (2014) Proc Natl Acad Sci U S A 111, 693-8 . Mak H, et al. (2012)BMC Cancer 12, 82. Heiska L, et al. (2011)Oncogene 30, 4953-62 . Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: EZR Research Areas: Cancer;Signal transduction