Phospho-CDC25C (Ser198) Antibody

Size : 100 µL Clone Number: Aliases: CDC 25 antibody; Cdc 25C antibody; CDC25 antibody; CDC25C antibody; Cell division cycle 25 homolog C antibody; Cell division cycle 25C antibody; Cell division cycle 25C protein antibody; Dual specificity phosphatase Cdc25C antibody; M phase inducer phosphatase 3 antibody; M-phase inducer phosphatase 3 antibody; Mitosis inducer CDC25 antibody; MPIP3 antibody; MPIP3_HUMAN antibody; Phosphotyrosine phosphatase antibody; PPP1R60 antibody; protein phosphatase 1, regulatory subunit 60 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P30307 Immunogen: Peptide sequence around phosphorylation site of Serine 198(E-F-S(p)-L-K) derived from Human CDC25C. Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; IHC: 1: 50-1: 100 Background: cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. Sadhu K., Proc. Natl. Acad. Sci. U.S.A. 87: 5139-5143(1990). Bureik M., Int. J. Oncol. 17: 1251-1258(2000). Wegener S., Eur. J. Cell Biol. 79: 810-815(2000). Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CDC25C Research Areas: Epigenetics and Nuclear Signaling;Cell biology