Phospho-EFNB2 (Tyr316) Antibody

Size : 100 µL Clone Number: Aliases: EFN B2 antibody; EFNB 2 antibody; Efnb2 antibody; EFNB2_HUMAN antibody; Eph related receptor tyrosine kinase ligand 5 antibody; EPH-related receptor tyrosine kinase ligand 5 antibody; ephrin B2 antibody; Ephrin-B2 antibody; EphrinB2 antibody; EPLG 5 antibody; EPLG5 antibody; Htk L antibody; HTK ligand antibody; HTK-L antibody; HTKL antibody; LERK 5 antibody; LERK-5 antibody; LERK5 antibody; Ligand of eph related kinase 5 antibody; MGC126226 antibody; MGC126227 antibody; MGC126228 antibody; OTTMUSP00000024973 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P52799 Immunogen: Peptide sequence around phosphorylation site of tyrosine 316 (P-V-Y(p)-I-V) derived from Human Ephrin-B2 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB; WB: 1: 500-1: 1000 Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. Chrencik JE,et al.( 2006) J Biol Chem;281(38): 28185-28192. Kertesz N, et al.( 2006) Blood;107(6): 2330-2338. Noren NK, et al.( 2004) Proc Natl Acad Sci USA;101(15): 5583-5588 Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjugate: Non-conjugated Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: EFNB2 Research Areas: Neuroscience?Cancer Cardiovascular