ARHGEF10 Antibody

Size : 50 µL Clone Number: Aliases: ARHGA_HUMAN antibody; ARHGEF10 antibody; DKFZp686H0726 antibody; GEF10 antibody; KIAA0294 antibody; MGC131664 antibody; Rho guanine nucleotide exchange factor (GEF) 10 antibody; Rho guanine nucleotide exchange factor 10 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O15013 Immunogen: Fusion protein of Human ARHGEF10 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, IHC; ELISA: 1: 2000-1: 5000, IHC: 1: 50-1: 200 Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. ARHGEF10 (rho guanine nucleotide exchange factor 10), also known as GEF10 or KIAA0294, is a 1,369 amino acid protein that contains one DBL-homology domain and is thought to play a role in myelination of peripheral nerves, specifically during development. ARHGEF10 is expressed as four alternatively spliced isoforms that are present at low levels in ovary, lung, testis and kidney, with considerably higher expression in the central and peripheral nervous systems. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ARHGEF10 Research Areas: Signal transduction