Phospho-HBP1 (Ser402) Antibody

Size : 100 µL Clone Number: Aliases: FLJ16340 antibody; HBP 1 antibody; HBP1 antibody; HBP1_HUMAN antibody; High mobility group box transcription factor 1 antibody; HMG box containing protein 1 antibody; HMG box transcription factor 1 antibody; HMG box-containing protein 1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O60381 Immunogen: Peptide sequence around phosphorylation site of serine 402 (C-G-S(p)-P-G) derived from Human HBP1. Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB; WB: 1: 500-1: 3000 Background: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: HBP1 Research Areas: Epigenetics and Nuclear Signaling;Cardiovascular;Stem cells