Phospho-CSNK2A1 (Thr360/Ser362) Antibody

Size : 100 µL Clone Number: Aliases: Casein kinase 2 alpha 1 polypeptide antibody; Casein kinase II alpha 1 antibody; Casein kinase II alpha 1 subunit antibody; Casein kinase II alpha subunit antibody; Casein kinase II subunit alpha antibody; CK II alpha antibody; CK II antibody; CK2 alpha antibody; CK2 catalytic subunit alpha antibody; CK2A1 antibody; CKII antibody; CKIIalpha antibody; CSK21_HUMAN antibody; CSNK2A1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P68400 Immunogen: Peptide sequence around phosphorylation site of threonine360/serine 362 (V-P-T(p)-P-S(p)-P-L) derived from Human CK2a. Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB; WB: 1: 500-1: 1000 Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The a and a' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation. Keller D.M., Zeng X., et al., Mol. Cell 7: 283-292(2001) Keller D.M., Lu H. et al., J. Biol. Chem. 277: 50206-50213(2002) Trembley J.H., Tatsumi S., et al., Mol. Cell. Biol. 25: 1446-1457(2005) Niefind K., Guerra B., et al., Acta Crystallogr. D 56: 1680-1684(2000) Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CSNK2A1 Research Areas: Cell biology;Signal transduction