Phospho-HCLS1 (Tyr397) Antibody

Size : 100 µL Clone Number: Aliases: Cortactin like antibody; CTTNL antibody; HCLS 1 antibody; Hcls1 antibody; HCLS1_HUMAN antibody; Hematopoietic cell specific Lyn substrate 1 antibody; Hematopoietic cell-specific LYN substrate 1 antibody; Hematopoietic lineage cell-specific protein antibody; HS 1 antibody; HS1 antibody; LckBP1 antibody; OTTHUMP00000215180 antibody; OTTHUMP00000215182 antibody; p75 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P14317 Immunogen: Peptide sequence around phosphorylation site of tyrosine 397(G-D-Y(p)-E-E) derived from Human HS1 . Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB; WB: 1: 500-1: 1000 Background: Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. Directly associates with HAX-1, through binding to its C-terminal region. May also be involved in the regulation of gene expression. Kitamura D., Nucleic Acids Res. 17: 9367-9379(1989). Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Ota T., Nat. Genet. 36: 40-45(2004). Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: HCLS1 Research Areas: Signal transduction