Phospho-HDAC7 (Ser155) Antibody

Size : 100 µL Clone Number: Aliases: DKFZP586J0917 antibody; FLJ99588 antibody; HD 7a antibody; HD7 antibody; HD7a antibody; HDAC 7 antibody; HDAC 7A antibody; Hdac7 antibody; HDAC7_HUMAN antibody; HDAC7A antibody; Histone deacetylase 7 antibody; Histone deacetylase 7A antibody; OTTHUMP00000202813 antibody; OTTHUMP00000202814 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q8WUI4 Immunogen: Peptide sequence around phosphorylation site of Serine 155(T-V-S(p)-E-P) derived from Human HDAC7A. Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB; WB: 1: 500-1: 1000 Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Walsh M.J., Submitted (FEB-2000). Zelent A., Submitted (MAY-2003). Sugano S., Nat. Genet. 36: 40-45(2004) Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: HDAC7 Research Areas: Epigenetics and Nuclear Signaling;Cardiovascular;Stem cells