Phospho-IRAK1 (Ser376) Antibody

Size : 100 µL Clone Number: Aliases: AA48924 antibody; Il1rak antibody; Interleukin 1 receptor associated kinase 1 antibody; Interleukin-1 receptor-associated kinase 1 antibody; IRAK antibody; IRAK-1 antibody; Irak1 antibody; IRAK1-S antibody; IRAK1_HUMAN antibody; mPLK antibody; OTTHUMP00000026014 antibody; OTTHUMP00000026015 antibody; OTTHUMP00000026020 antibody; OTTHUMP00000180621 antibody; Pelle antibody; Pelle homolog antibody; Pelle-like protein kinase antibody; Plpk antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P51617 Immunogen: Peptide sequence around phosphorylation site of Serine 376(Q-S-S(p)-M-V) derived from Human IRAK1. Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; IHC: 1: 50-1: 100 Background: IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Cao Z., Science 271: 1128-1131(1996). Reichwald K., Mamm. Genome 11: 182-190(2000). Jensen L.E., J. Biol. Chem. 276: 29037-29044(2001). Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: IRAK1 Research Areas: Cardiovascular;Immunology;Signal transduction