Phospho-CTBP1 (Ser422) Antibody

Size : 100 µL Clone Number: Aliases: BARS antibody; brefeldin A- ribosylated substrate antibody; C terminal binding protein 1 antibody; C-terminal-binding protein 1 antibody; CTBP antibody; CtBP1 antibody; CTBP1_HUMAN antibody; MGC104684 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q13363 Immunogen: Peptide sequence around phosphorylation site of Serine 422(A-P-S(p)-P-G) derived from Human CtBP1. Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; WB: 1: 500-1: 1000, IHC: 1: 50-1: 100 Background: This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92: 10467-10471(1995). Sewalt R.G.A.B., Mol. Cell. Biol. 19: 777-787(1999). The MGC Project Team, Genome Res. 14: 2121-2127(2004). Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CTBP1 Research Areas: Epigenetics and Nuclear Signaling;Cancer;Cell biology;Microbiology