Phospho-CCDC88A (Ser1417) Antibody
Size : 100 µL
Clone Number:
Aliases: AKT iphosphorylation enhancer antibody; Akt phosphorylation enhancer antibody; APE antibody; Ccdc88a antibody; Coiled coil domain containing 88A antibody; Coiled coil domain containing protein 88A antibody; Coiled-coil domain-containing protein 88A antibody; FLJ10392 antibody; G alpha interacting vesicle associated protein antibody; G alpha-interacting vesicle-associated protein antibody; Galpha interacting vesicle associated protein antibody; Girders of actin filament antibody; Girdin antibody; GIV antibody; GRDN antibody; GRDN_HUMAN antibody; HkRP1 antibody; Hook related protein 1 antibody; Hook-related protein 1 antibody; KIAA1212 antibody
Product Type: Polyclonal Antibody
Immunogen Species: Homo sapiens (Human)
UniProt ID: Q3V6T2
Immunogen: Peptide sequence around phosphorylation site of Serine 417(L-E-M(p)-A-Q) derived from Human Girdin .
Host: Rabbit
Reactivity: Human, Mouse
Tested Applications: ELISA, IHC; IHC: 1: 50-1: 100
Background:
girdin IS a ubiquitously expressed actin binding protein that plays an important role in the formation of stress fibers and lamellipodia. Subsequent to phosphorylation by Akt, Girdin accumulates at the leading edge of migrating cells and appears to be crucial for the integrity of the actin cytoskeleton and for cell migration.
Enomoto A., Dev. Cell 9: 389-402(2005).
Simpson F., Traffic 6: 442-458(2005).
Hillier L.W., Nature 434: 724-731(2005).
Clonality: Polyclonal
Isotype: IgG
Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Conjugate: Non-conjugated
Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names: CCDC88A
Research Areas: Neuroscience;Signal transduction