Phospho-IGFBP3 (Ser183) Antibody

Size : 100 µL Clone Number: Aliases: Acid stable subunit of the 140 K IGF complex antibody; Binding protein 29 antibody; Binding protein 53 antibody; BP 53 antibody; BP53 antibody; Growth hormone dependent binding protein antibody; IBP 3 antibody; IBP-3 antibody; IBP3 antibody; IBP3_HUMAN antibody; IGF binding protein 3 antibody; IGF-binding protein 3 antibody; IGFBP 3 antibody; IGFBP-3 antibody; IGFBP3 antibody; Insulin Like Growth Factor Binding Protein 3 antibody; Insulin-like growth factor binding protein 3 precursor antibody; Insulin-like growth factor-binding protein 3 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P17936 Immunogen: Peptide sequence around phosphorylation site of serine 183(K-D-S(p)-Q-R) derived from Human IGFBP-3 . Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB; WB: 1: 500-1: 1000 Background: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Zhang Q, Steinle JJ (2013)Invest Ophthalmol Vis Sci 54, 3052-7 . Cobb LJ, Liu B, Lee KW, Cohen P (2006) Cancer Res 66, 10878-84 . Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: IGFBP3 Research Areas: Cancer Cardiovascular?Cell biology;Metabolism;Signal transduction