Phospho-CEBPA (Thr230) Antibody

Size : 100 µL Clone Number: Aliases: Apoptotic cysteine protease antibody; Apoptotic protease Mch 5 antibody; C/EBP alpha antibody; C/ebpalpha antibody; CAP4 antibody; Caspase 8 precursor antibody; CBF-A antibody; CCAAT Enhancer Binding Protein alpha antibody; CCAAT/enhancer binding protein (C/EBP); alpha antibody; CCAAT/enhancer-binding protein alpha antibody; CEBP antibody; CEBP A antibody; CEBP alpha antibody; Cebpa antibody; CEBPA_HUMAN antibody; FADD homologous ICE/CED 3 like protease antibody; FADD like ICE antibody; FLICE antibody; ICE like apoptotic protease 5 antibody; ICE8 antibody; MACH antibody; MCH5 antibody; MORT1 associated CED 3 homolog antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P49715 Immunogen: Peptide sequence around phosphorylation site of threonine 230 (P-P-T(p)-P-V) derived from Human C/EBP-?. Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB; WB: 1: 500-1: 1000 Background: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.Xanthopoulos K.G. Biochem. Biophys. Res. Commun. 215: 106-113(1995)Schalwijk J. Biol. Chem. Hoppe-Seyler 378: 373-379(1997)SeattleSNPs variation discovery resource Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CEBPA Research Areas: Epigenetics and Nuclear Signaling;Cancer Cardiovascular;Metabolism;Signal transduction