Phospho-FCGR2B (Tyr292) Antibody

Size : 100 µL Clone Number: Aliases: CD32 antibody; CD32 antigen antibody; CD32B antibody; CDw32 antibody; Fc fragment of IgG; low affinity II; receptor for (CD32) antibody; Fc fragment of IgG; low affinity IIb; receptor antibody; Fc fragment of IgG; low affinity IIb; receptor (CD32) antibody; Fc fragment of IgG; low affinity IIb; receptor for (CD32) antibody; Fc fragment of IgG; low affinity IIb; receptor for antibody; Fc gamma receptor IIB antibody; Fc gamma RII antibody; Fc gamma RIIB antibody; Fc-gamma RII antibody; Fc-gamma RII-b antibody; Fc-gamma-RIIb antibody; FCG2 antibody; FCG2B_HUMAN antibody; Fcgr2 antibody; FCGR2B antibody; FCRII antibody; FcRII-b antibody; IGFR2 antibody; IgG Fc receptor II beta antibody; IgG Fc receptor II-b antibody; Low affinity immunoglobulin gamma Fc region receptor II antibody; Low affinity immunoglobulin gamma Fc region receptor II-b antibody; Ly-17 antibody; Lym 1 antibody; Lymphocyte antigen 17 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P31994 Immunogen: Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32. Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB; WB: 1: 500-1: 1000 Background: Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. Stuart S.G., EMBO J. 8: 3657-3666(1989). Brooks D.G., J. Exp. Med. 170: 1369-1385(1989). Engelhardt W., Eur. J. Immunol. 20: 1367-1377(1990). Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: FCGR2B Research Areas: Immunology;Stem cells