Phospho-GRIA2 (Ser880) Antibody

Size : 100 µL Clone Number: Aliases: AMPA 2 antibody; AMPA selective glutamate receptor 2 antibody; AMPA-selective glutamate receptor 2 antibody; AMPA2 antibody; GluA2 antibody; GLUR 2 antibody; GLUR B antibody; GluR K2 antibody; GluR-2 antibody; GluR-B antibody; GluR-K2 antibody; GLUR2 antibody; GLURB antibody; Glutamate receptor 2 antibody; Glutamate receptor ionotropic AMPA 2 antibody; Glutamate receptor ionotropic antibody; Gria2 antibody; GRIA2_HUMAN antibody; HBGR2 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P42262 Immunogen: Peptide sequence around phosphorylation site of serine 880 (I-E-S(p)-V-K) derived from Human Glutamate receptor 2. Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB; WB: 1: 500-1: 1000 Background: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Cull-Candy, S. et al. (2006) Curr. Opin. Neurobiol. 16, 288-297. Hanley JG, et al. (2002) Neuron. 34(1): 53-67 Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: GRIA2 Research Areas: Neuroscience