Phospho-CCR5 (Ser349) Antibody

Size : 100 µL Clone Number: Aliases: AM4 7 antibody; C C chemokine receptor type 5 antibody; C C CKR 5 antibody; C-C chemokine receptor type 5 antibody; C-C CKR-5 antibody; C-C motif chemokine receptor 5 A159A antibody; CC Chemokine Receptor 5 antibody; CC Chemokine Receptor Type 5 antibody; CC CKR 5 antibody; CC-CKR-5 antibody; CCCKR 5 antibody; CCCKR5 antibody; CCR 5 antibody; CCR-5 antibody; CCR5 antibody; CCR5 chemokine (C C motif) receptor 5 antibody; CCR5_HUMAN antibody; CD 195 antibody; CD195 antibody; CD195 Antigen antibody; Chemokine C C motif receptor 5 antibody; Chemokine receptor CCR5 antibody; CHEMR13 antibody; CKR 5 antibody; CKR5 antibody; CMKBR 5 antibody; CMKBR5 antibody; FLJ78003 antibody; HIV 1 Fusion Coreceptor antibody; HIV-1 fusion coreceptor antibody; HIV1 fusion coreceptor antibody; IDDM22 antibody; MIP-1 alpha receptor antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P51681 Immunogen: Peptide sequence around phosphorylation site of Serine 349 (E-I-S(p)-V-G) derived from Human CCR5. Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB; WB: 1: 500-1: 1000 Background: Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates. Martin Oppermann, J. Biol. Chem., Mar 1999; 274: 8875. Beatrix Pollok-Kopp, J. Biol. Chem., Jan 2003; 278: 2190 - 2198. Ramtin Rahbar, J. Virol., Jul 2006; 80: 7245 - 7259. H Olbrich, J. Leukoc. Biol., Mar 1999; 65: 281. Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CCR5 Research Areas: Neuroscience?Cancer Cardiovascular;Immunology;Microbiology?Signal transduction