Phospho-CAV2 (Tyr27) Antibody

Size : 100 µL Clone Number: Aliases: CAV antibody; CAV2 antibody; CAV2_HUMAN antibody; Caveolae protein 20 kD antibody; Caveolin 2 antibody; Caveolin 2 isoform a and b antibody; Caveolin-2 antibody; MGC12294 antibody; OTTHUMP00000025032 antibody; OTTHUMP00000195982 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P51636 Immunogen: Peptide sequence around phosphorylation site of tyrosine 27 (L-E-Y(p)-A-D) derived from Human Caveolin 2. Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB; WB: 1: 500-1: 1000 Background: The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript. Scherer P.E., Proc. Natl. Acad. Sci. U.S.A. 93: 131-135(1996). Scherer P.E., J. Biol. Chem. 272: 29337-29346(1997). Engelman J.A., FEBS Lett. 448: 221-230(1999). Clonality: Polyclonal Isotype: IgG Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CAV2 Research Areas: Cardiovascular;Tags & Cell Markers