Aggrecan antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Aggrecan(ACAN), also named as CSPCP, AGC1 and MSK16, belongs to the aggrecan/versican proteoglycan family(also including versican, brevican and neurocan). It is a major component of extracellular matrix of cartilagenous tissues. A major function of aggrecan is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. This polyclonal antibody raised against 1-298aa of human aggrecan reveals a band of 70 kDa, which is consistent with the molecular weight of degradation product generated by proteolysis at the aggrecanase site(PMID: 7852317; 9337874). Immunogen: aggrecan Synonyms: ACAN, AGC1, AGCAN, aggrecan, CSPG1, CSPGCP, MSK16, SEDK Observed MW: 70 kDa Uniprot ID: P16112 Reactivity: Human, Mouse, Rat Tested Application: ELISA, WB, IHC Recommended dilution: WB: 1: 500-1: 1000; IHC: 1: 20-1: 200 Gene ID: Research Area: Stem Cells, Cardiovascular, Metabolism, Developmental biology