ARHGEF7 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Acts as a RAC1 guanine nucleotide exchange factor(GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions(By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons. Immunogen: Rho guanine nucleotide exchange factor(GEF) 7 Synonyms: COOL1, KIAA0142, P85SPR, PAK3BP, PIXB Observed MW: 70 kDa Uniprot ID: Q14155 Reactivity: Human, Mouse, Rat Tested Application: ELISA, IP, WB Recommended dilution: WB: 1: 1000-1: 4000; IP: 1: 500-1: 2000 Gene ID: 8874 Research Area: Signal Transduction